Research Authors

Overview

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Glutathione (Reduced Form)
500 mg
**
Milk Thistle Extract (Silybum marianum) (Fruit/Seeds) (Standardized to 80 mg Silymarin Flavonoids - equivalent 80%)
100 mg
**
Alpha Lipoic Acid
50 mg
**

Top Medical Research Studies

9
Extracts reduce kidney stone formation
We investigated the potential of Cymbopogon proximus (Halfa Bar) and Petroselinum crispum (parsley) seed extracts in reducing kidney stones, using a rigorous study design involving multiple groups of rats. One group received a mixture of ethylene glycol and ammonium chloride to induce urolithiasis, a condition characterized by kidney stone formation. In contrast, other groups received treatment either as an emulsion or a nanogel form of the extracts.

During the trials, we observed that the urolithiasis model led to a troubling decrease in essential kidney health indicators such as urinary magnesium levels and specific antioxidant activities, including glutathione and catalase. Additionally, we noted an increase in harmful substances that often contribute to stone formation, like calcium and oxalate crystals.

Interestingly, treatment with either the emulsion or the nanogel significantly improved these kidney indicators. It elevated glutathione levels and reduced the formation of oxalate crystals, all while enhancing kidney function. The nanogel version of the extracts showed even better results compared to the traditional emulsion, suggesting a promising avenue for further research.

In conclusion, our findings indicate that the extracts from C. proximus and P. crispum can indeed assist in protecting against kidney stones by supporting kidney function and minimizing unhealthy kidney changes. While glutathione played a role in this context, it was part of a broader treatment strategy, making its isolated effects harder to pinpoint.
Read More

Most Useful Reviews

2
Potential kidney impact
The price is excellent, but after taking two pills daily, they ran out in a month. I realised this affected my kidneys, so caution is advised.
Read More
4
Kidney function caution
A good experience; I bought it based on my sisters' recommendation. The results are promising, but I initially took two pills, which negatively affected my kidney function. So, be cautious with dosages and drink plenty of water.
Read More
2
Cleaning effect only
I didn't see any results from this product. It seems to only clean the kidneys and has average quality. It lasts a long time, but the taste is non-existent.
Read More

Medical Researches

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
  • All Researches
9
Extracts reduce kidney stone formation
We investigated the potential of Cymbopogon proximus (Halfa Bar) and Petroselinum crispum (parsley) seed extracts in reducing kidney stones, using a rigorous study design involving multiple groups of rats. One group received a mixture of ethylene glycol and ammonium chloride to induce urolithiasis, a condition characterized by kidney stone formation. In contrast, other groups received treatment either as an emulsion or a nanogel form of the extracts.

During the trials, we observed that the urolithiasis model led to a troubling decrease in essential kidney health indicators such as urinary magnesium levels and specific antioxidant activities, including glutathione and catalase. Additionally, we noted an increase in harmful substances that often contribute to stone formation, like calcium and oxalate crystals.

Interestingly, treatment with either the emulsion or the nanogel significantly improved these kidney indicators. It elevated glutathione levels and reduced the formation of oxalate crystals, all while enhancing kidney function. The nanogel version of the extracts showed even better results compared to the traditional emulsion, suggesting a promising avenue for further research.

In conclusion, our findings indicate that the extracts from C. proximus and P. crispum can indeed assist in protecting against kidney stones by supporting kidney function and minimizing unhealthy kidney changes. While glutathione played a role in this context, it was part of a broader treatment strategy, making its isolated effects harder to pinpoint.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 3 Reviews
7.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
2
Potential kidney impact
The price is excellent, but after taking two pills daily, they ran out in a month. I realised this affected my kidneys, so caution is advised.
Read More
4
Kidney function caution
A good experience; I bought it based on my sisters' recommendation. The results are promising, but I initially took two pills, which negatively affected my kidney function. So, be cautious with dosages and drink plenty of water.
Read More
2
Cleaning effect only
I didn't see any results from this product. It seems to only clean the kidneys and has average quality. It lasts a long time, but the taste is non-existent.
Read More

Frequently Asked Questions

4
Kidney function caution
A good experience; I bought it based on my sisters' recommendation. The results are promising, but I initially took two pills, which negatively affected my kidney function. So, be cautious with dosages and drink plenty of water.
2
Cleaning effect only
I didn't see any results from this product. It seems to only clean the kidneys and has average quality. It lasts a long time, but the taste is non-existent.
2
Potential kidney impact
The price is excellent, but after taking two pills daily, they ran out in a month. I realised this affected my kidneys, so caution is advised.
9
Extracts reduce kidney stone formation
We investigated the potential of Cymbopogon proximus (Halfa Bar) and Petroselinum crispum (parsley) seed extracts in reducing kidney stones, using a rigorous study design involving multiple groups of rats. One group received a mixture of ethylene glycol and ammonium chloride to induce urolithiasis, a condition characterized by kidney stone formation. In contrast, other groups received treatment either as an emulsion or a nanogel form of the extracts.

During the trials, we observed that the urolithiasis model led to a troubling decrease in essential kidney health indicators such as urinary magnesium levels and specific antioxidant activities, including glutathione and catalase. Additionally, we noted an increase in harmful substances that often contribute to stone formation, like calcium and oxalate crystals.

Interestingly, treatment with either the emulsion or the nanogel significantly improved these kidney indicators. It elevated glutathione levels and reduced the formation of oxalate crystals, all while enhancing kidney function. The nanogel version of the extracts showed even better results compared to the traditional emulsion, suggesting a promising avenue for further research.

In conclusion, our findings indicate that the extracts from C. proximus and P. crispum can indeed assist in protecting against kidney stones by supporting kidney function and minimizing unhealthy kidney changes. While glutathione played a role in this context, it was part of a broader treatment strategy, making its isolated effects harder to pinpoint.

References

  1. Essa HA, Ali AM, Saied MA. Cymbopogon proximus and Petroselinum crispum seed ethanolic extract/Gum Arabic nanogel emulsion: Preventing ethylene glycol and ammonium chloride-induced urolithiasis in rats. Urolithiasis. 2024;52:52. 10.1007/s00240-024-01559-2
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